John F Engelhardt Selected Research

pervanadate

1/2003	Tyrosine phosphorylation of I kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation.
12/2002	Temporal pattern of NFkappaB activation influences apoptotic cell fate in a stimuli-dependent fashion.

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John F Engelhardt Research Topics

Disease

29	Cystic Fibrosis (Mucoviscidosis) 10/2022 - 01/2002
17	Infections 01/2018 - 03/2002
6	Lung Diseases (Lung Disease) 01/2020 - 12/2004
6	Neoplasms (Cancer) 01/2018 - 04/2002
6	Hypoxia (Hypoxemia) 07/2013 - 12/2002
4	Bacterial Infections (Bacterial Infection) 01/2019 - 11/2003
4	Inflammation (Inflammations) 01/2016 - 03/2004
4	Ischemia 07/2013 - 03/2003
4	Wounds and Injuries (Trauma) 06/2009 - 12/2002
3	Hyperglycemia 08/2021 - 01/2016
3	Respiratory Tract Infections (Respiratory Tract Infection) 01/2020 - 10/2015
3	Disease Progression 11/2016 - 07/2009
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2011 - 02/2008
3	Hypertension (High Blood Pressure) 07/2007 - 11/2003
2	Fibrosis (Cirrhosis) 10/2022 - 02/2010
2	Insulin Resistance 08/2021 - 01/2014
2	Virus Diseases (Viral Diseases) 01/2021 - 10/2015
2	Inborn Genetic Diseases (Disease, Hereditary) 10/2019 - 11/2013
2	Glucose Intolerance 01/2019 - 01/2015
2	Dehydration (Water Stress) 01/2019 - 04/2016
2	Pancreatic Diseases (Pancreatic Disease) 01/2018 - 08/2008
2	Reperfusion Injury 03/2008 - 03/2003
2	Necrosis 01/2007 - 03/2003
2	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 11/2005 - 03/2002
1	Chronic Disease (Chronic Diseases) 10/2022
1	B-Cell Lymphoma (Lymphoma, B Cell) 10/2022
1	Obstructive Lung Diseases (Obstructive Lung Disease) 01/2022
1	Edema (Dropsy) 08/2021
1	Pancreatitis 08/2021
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2021
1	Herpes Zoster 01/2018
1	Bronchiolitis 01/2018
1	Diabetes Mellitus 11/2016
1	Hereditary pancreatitis 11/2016

Drug/Important Bio-Agent (IBA)

17	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 10/2022 - 01/2002
9	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2016 - 11/2003
6	Proteins (Proteins, Gene)FDA Link 01/2018 - 03/2004
5	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2015
5	Chloride Channels (Chloride Channel)IBA 04/2016 - 08/2011
5	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2013 - 03/2003
5	NF-kappa B (NF-kB)IBA 05/2008 - 01/2003
4	Insulin (Novolin)FDA Link 08/2021 - 01/2014
4	Viral DNAIBA 01/2021 - 01/2016
4	Messenger RNA (mRNA)IBA 01/2020 - 12/2002
4	CytokinesIBA 12/2017 - 01/2007
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2009 - 12/2002
3	Small Interfering RNA (siRNA)IBA 12/2017 - 08/2006
3	ChloridesIBA 05/2016 - 09/2010
3	NF-KappaB Inhibitor alphaIBA 05/2008 - 12/2002
3	Superoxides (Superoxide)IBA 08/2006 - 04/2002
3	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2004 - 03/2002
2	Amylases FDA Link 08/2021 - 01/2018
2	Complement System Proteins (Complement)IBA 01/2020 - 06/2015
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2018 - 03/2014
2	Phosphotransferases (Kinase)IBA 01/2017 - 01/2016
2	A-Form DNA (A-DNA)IBA 01/2017 - 01/2016
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2017 - 01/2016
2	Antiviral Agents (Antivirals)IBA 01/2017 - 01/2016
2	Proteasome InhibitorsIBA 09/2013 - 07/2003
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 03/2008 - 03/2003
2	Oxidoreductases (Dehydrogenase)IBA 07/2007 - 09/2004
2	EndotoxinsIBA 01/2007 - 03/2004
2	DystrophinIBA 11/2005 - 03/2002
2	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2004 - 03/2004
2	Superoxide DismutaseIBA 12/2004 - 04/2002
2	pervanadateIBA 01/2003 - 12/2002
2	Tyrosine (L-Tyrosine)FDA Link 01/2003 - 12/2002
2	Transcription Factors (Transcription Factor)IBA 01/2003 - 12/2002
1	complement C4dIBA 10/2022
1	Immunoglobulins (Immunoglobulin)IBA 10/2022
1	Interleukin-6 (Interleukin 6)IBA 08/2021
1	Lipase (Acid Lipase)FDA Link 08/2021
1	Hypoglycemic Agents (Hypoglycemics)IBA 08/2021
1	CeruletideIBA 08/2021
1	Growth Hormone (Somatotropin)IBA 01/2019
1	ivacaftorIBA 01/2019
1	MucinsIBA 01/2019
1	acyl-ghrelinIBA 01/2019
1	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2019
1	IncretinsIBA 01/2019
1	Bicarbonates (Hydrogen Carbonate)IBA 01/2018
1	ChromograninsIBA 01/2018
1	Keratin-5 (Keratin 5)IBA 01/2018
1	CateninsIBA 01/2018
1	InflammasomesIBA 12/2017
1	Interleukin-1 (Interleukin 1)IBA 12/2017
1	Interleukin-18 (Interleukin 18)IBA 12/2017
1	InterleukinsIBA 12/2017
1	Pattern Recognition ReceptorsIBA 12/2017
1	Caspase 3 (Caspase-3)IBA 12/2017
1	DNA (Deoxyribonucleic Acid)IBA 01/2017
1	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 01/2017
1	TrypsinogenIBA 11/2016
1	CathepsinsIBA 04/2016
1	Cystatin CIBA 04/2016
1	AdiponectinIBA 01/2016

Therapy/Procedure

14	Therapeutics 01/2022 - 12/2004
2	Lung Transplantation 10/2022 - 01/2018
1	Glycemic Control 01/2018
1	Pain Management 11/2016